"Mission Possible" takes a look at the living conditions of Nevilla "Ebing" Macapagal and her three mentally ill children. Macapagal relates the difficulties in raising her children who suffer from the condition called global developmental delay. Autism Society Philippines-Pampanga Chapter president Joyla Ofrecia and MWSD-San Simon Pampanga social welfare officer Everlita Baluyut visit Macapagal's home to assess how they can offer assistance to her family. The program brings Macapagal and her children to an eye doctor and a psychologist to have their health checked. Lastly, generous donors give home appliances and grocery items to Nanay Ebing.