Born Luis Philippe Santos Manzano, Luis Manzano is the son of Edu Manzano and Vilma Santos. Growing up, he was more popularly known as Lucky. Senator Ralph Recto is his stepfather. Luis also has three half siblings, two on his father's side and one on his mother's side. Luis started his career by modelling for a very popular clothing brand in the Philippines. He starting his hosting and acting career with ABS-CBN and is one of the longest serving VJs on MYY Philippines. One of his more popular movie roles was playing gay man, Mark Salavacion, alongside John Lloyd Cruz in In My Life where his real life mother Vilma Santos played the role of his mother. Luis Manzano is also one of ABS-CBN's hosts for many of its reality and gameshow programs. Luis is currently hosting Celebrity Playtime, Kapamilya Deal or No Deal and will be a co-host for the fifth season of Pilipinas Got Talent.